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Grant - Summer 2015 - ALS - Don Cleveland, Ph.D.

Don Cleveland, distinguished professor and chair in the department of cellular and molecular medicine at the University of California, San Diego, in La Jolla, was awarded an MDA research grant totaling $300,000 over three years to elucidate the mechanisms of ALS (amyotrophic lateral sclerosis)caused by mutations in the Fused in Sarcoma (FUS) gene. Cleveland and colleagues will be using newly developed mouse models to investigate whether alterations in the FUS gene cause ALS by a loss of the normal function of the FUS protein or through adoption of a new, toxic function of the protein. A better appreciation of how FUS alterations cause motor neuron death will aid in determining what type of treatment approach may work best for this type of ALS.
Funding for this ALS research grant began Aug. 1, 2015.
Grantee: ALS - Don Cleveland, Ph.D.
Grant type: Research Grant
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