
Hope Through Research
At MDA, we take a big picture perspective across the full spectrum of neuromuscular diseases to uncover scientific and medical breakthroughs that accelerate treatments and cures. The power in our research approach is that we can often apply learnings from one disease to progress in others to bring urgently-needed answers to our families.
Winter Grants 2018
-
DMD – Matthew Alexander, Ph.D.
Funded: 02/01/18 through 01/31/21Grant Announced: Winter 2018Disease Type: Duchenne Muscular Dystrophy (DMD)“Many drugs for neuromuscular diseases fail to win FDA approval, resulting in a large amount of wasted time and resources...”
-
Myofibrillar Myopathy – Robert Bryson-Richardson, Ph.D.
Funded: 02/01/18 through 01/31/20Grant Announced: Winter 2018Disease Type: Myofibrillar Myopathies (MFM)“We are testing multiple drugs in our animal model,” Robert Bryson-Richardson said. “Some of these, if effective, cou...”
-
ALS – Fatima Gasset-Rosa, Ph.D.
Funded: 02/01/18 through 01/31/18Grant Announced: Winter 2018Disease Type: Amyotrophic Lateral Sclerosis (ALS)“I believe that understanding the initial event that provokes TDP-43 abnormalities and TDP-43 spread within the nervous s...”
-
DMD – David Hammers, Ph.D.
Funded: 02/01/18 through 01/31/21Grant Announced: Winter 2018Disease Type: Duchenne Muscular Dystrophy (DMD)“The development of effective therapeutics to target fibrosis is greatly needed to increase both the quality and quantity...”
-
CCD – Amy Hanna, Ph.D.
Funded: 02/01/18 through 01/31/21Grant Announced: Winter 2018Disease Type: Congenital Myopathies“Hanna’s work is aimed at shedding light on how ryanodine receptor and calsequestrin mutations that alter calcium handl...”
-
CMD – Dwi Kemaladewi, Ph.D.
Funded: 02/01/18 through 02/01/21Grant Announced: Winter 2018Disease Type: Congenital Muscular Dystrophy (CMD)“Successful completion of this project will provide us with the necessary preclinical data and comprehensive strategy to ...”
-
FA – David Lynch, M.D., Ph.D.
Funded: 02/01/18 through 01/31/21Grant Announced: Winter 2018Disease Type: Friedreich's Ataxia (FA)“Several therapies in clinical trials have shown an unexpected immediate benefit — of days to a few weeks — especiall...”
-
LGMD + other NMDs – Daniel MacArthur, Ph.D.
Funded: 12/01/17 through 11/30/18Grant Announced: Winter 2018Disease Type: Limb-Girdle Muscular Dystrophy (LGMD)“The low prevalence of similar rare muscle disease patients means that recruiting for a study with in-person visits is of...”
-
Inclusion Body Myositis (IBM) + Pompe disease + CNM/MTM - Marta Margeta, M.D., Ph.D.
Funded: 02/01/18 through 01/31/20Grant Announced: Winter 2018Disease Type: Inclusion-Body Myositis (IBM)“Both autophagy impairment and excessive autophagy activation play a role in many human diseases including cancer and Par...”
-
ALS and DM – Lukasz Sznajder, MSc, Ph.D.
Funded: 02/01/18 through 01/31/18Grant Announced: Winter 2018Disease Type: Amyotrophic Lateral Sclerosis (ALS)“Novel therapeutic approaches for the neurological and neuromuscular diseases caused by the expansion of repetitive eleme...”
-
ALS – Target ALS
Funded: 12/01/17 through 08/01/18Grant Announced: Winter 2018Disease Type: Amyotrophic Lateral Sclerosis (ALS)“An urgent need exists in ALS research for biological indicators called biomarkers that can be used for diagnostic purpos...”
-
ALS – Kristi Wharton, Ph.D.
Funded: 01/01/18 through 06/30/18Grant Announced: Winter 2018Disease Type: Amyotrophic Lateral Sclerosis (ALS)“It is likely that success in identifying a therapeutic intervention, as well as a cure, will only come when the ability ...”
-
CMT – Stephan Zuchner, M.D., Ph.D.
Funded: 12/01/17 through 01/21/20Grant Announced: Winter 2018Disease Type: Charcot-Marie-Tooth Disease (CMT)“An open Charcot-Marie-Tooth genetics data resource could help expedite CMT research, from gene identification to drug di...”