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35 grants match your search

  • Umrao Monani, Ph.D.
    Funded: 09/01/23 through 08/31/26
    Grant Announced: 2023
    Disease Type: Spinal Muscular Atrophy (SMA)
     
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  • Identifying novel SMA-causing variants by NGS sequencing of the SMN1 locus – Matthew Avenarius, PhD
    Funded: 09/01/21 through 08/31/22
    Grant Announced: 2021
    Disease Type: Spinal Muscular Atrophy (SMA)
    “In nearly all cases, the genetic defect is caused by the inheritance of two deleted copies of SMN1, which can rapidly be...”
     
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  • SMA - Tomoyuki Awano, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Using a confocal microscope, Awano views a neuromuscular junction in a mouse gastrocnemius muscle. On the computer monit...”
     
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  • SMA - Gary Bassell, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Spinal Muscular Atrophy (SMA)
    ““Our central hypothesis is that SMN protein plays a critical role in facilitating regulation of mRNA transport in moto...”
     
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  • SMA — Lisa Baumbach, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Baumbach (front, right) with the other members of the lab team that discovered the X-linked gene for spinal muscular atr...”
     
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  • SMA - Arthur Burghes, PhD
    Funded: 08/01/19 through 07/31/21
    Grant Announced: Summer 2019
    Disease Type: Spinal Muscular Atrophy (SMA)
    “In this proposal we aim to identify the genes that modify the severity of SMA and the changes in them that cause modific...”
     
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  • SMA - Arthur Burghes, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Arthur Burghes is working to develop a new technique that will allow scientists to accurately predict the severity of a ...”
     
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  • SMA - Christine DiDonato, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Spinal Muscular Atrophy (SMA)
    “A and B: Side and abdominal views of a mouse walking on a transparent treadmill belt. C: A digital image of paw prints f...”
     
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  • SMA – Christine DiDonato, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Christine DiDonato aims to characterize the role of SMN protein in skeletal muscle. Her work could lead to development o...”
     
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  • SMA - Constantin d’Ydewalle, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Spinal Muscular Atrophy (SMA)
    “An MDA development grant jointly funded by MDA and the American Association of Neuromuscular & Electrodiagnostic Med...”
     
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  • SMA - Kevin Foust, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Kevin Foust is conducting the first investigation into the SMA gut microbiome — work that will provide a better unders...”
     
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  • Laxman Gangwani, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Laxman Gangwani’s MDA-supported work could lead to treatments for spinal muscular atrophy and other related neuromuscu...”
     
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  • Identification of modifier gene(s) of spinal muscular atrophy in model mice – Narendra Jha, PhD
    Funded: 09/01/21 through 08/31/24
    Grant Announced: 2021
    Disease Type: Spinal Muscular Atrophy (SMA)
    “While enhancing SMN as a means to treating SMA is undoubtedly a major development, the therapeutic strategy has its limi...”
     
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  • SMA - Stephen Kolb, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Stephen Kolb is determining how best to measure SMA progression during the first two years of life so that experimental ...”
     
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  • Rashmi Kothary, Ph.D.
    Funded: 09/01/22 through 08/31/25
    Grant Announced: 2022
    Disease Type: Spinal Muscular Atrophy (SMA)
     
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  • SMA - Rashmi Kothary, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Rashmi Kothary (center, standing) is investigating a new therapeutic avenue for SMA. Spinal Muscular Atrophy (SMA)”
     
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  • SMA – Rashmi Kothary, PhD
    Funded: 08/01/18 through 07/31/21
    Grant Announced: Summer 2018
    Disease Type: Spinal Muscular Atrophy (SMA)
    “There has to be great optimism about the emerging therapies for the treatment of SMA. There has been tremendous progress...”
     
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  • SMA - Christian Lorson, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Spinal Muscular Atrophy (SMA)
    “"SMA research is at an exciting stage," Lorson said. "While it is fully acknowledged that from a patient or family persp...”
     
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  • SMA - Chris Lorson, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    ““SMA is exceptionally well suited for therapeutic approaches that target SMN2; however, there currently is no FDA-appr...”
     
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  • SMA - John Manfredi, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Manfredi and colleagues have identified several small molecules that promote the growth of axons of motor neurons, which...”
     
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  • SMA — John Manfredi
    Grant Announced: Summer 2010
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Manfredi will study the effects of drug compounds designed to support motor neurons (nerve cells) in zebra fish that hav...”
     
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  • SMA - Steven Markus, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    ““The tools we have at our disposal to answer complex biological questions are becoming extremely sophisticated, and en...”
     
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  • SMA - Stephen Meriney, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Spinal Muscular Atrophy (SMA)
    “This project will directly test a novel treatment to address neuromuscular weakness in SMA patients. This treatment is n...”
     
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  • SMA — Umrao Monani, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Spinal Muscular Atrophy (SMA)
    “In this microscopic view of three different neuromuscular synapses, clusters of receptors have fragmented, one of the fi...”
     
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  • SMA – Jacqueline Montes, PT, EdD, NCS
    Funded: 04/01/18 through 04/30/21
    Grant Announced: Summer 2018
    Disease Type: Spinal Muscular Atrophy (SMA)
     
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  • SMA - Lyndsay Murray, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Lyndsay Murray (front) will investigate a potential new strategy for protecting nerve cells that carry SMA-causing abnor...”
     
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  • SMA – Lyndsay Murray, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    ““My lab works predominantly on mouse models of spinal muscular atrophy,” Lyndsay Murray says. “It is our goal to u...”
     
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  • SMA — Bennett Novitch, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Bennett Novitch is working to generate a better understanding of the development and health of muscle-controlling nerve ...”
     
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  • SMA - Franco Pagani, M.D.
    Grant Announced: Winter 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    ““Using a novel strategy based on small RNA, we intend to correct the splicing defect of the SMN2 gene,” Franco Pagan...”
     
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  • SMA - Livio Pellizzoni, M.D.
    Grant Announced: Winter 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Livio Pellizzoni is working to elucidate a new function of SMN protein, which is deficient in spinal muscular atrophy.”
     
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  • SMA - Natalia Rodriguez Muela, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Natalia Rodriguez Muela will examine how SMN protein levels are affected by autophagy, a cellular garbage disposal syste...”
     
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  • SMA - Kentaro Sahashi, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Spinal Muscular Atrophy (SMA)
    “With colleagues, Sahashi is investigating the use of antisense oligonucleotides (ASOs) in SMA therapies. The team also h...”
     
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  • SM - Claudio Sette, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Pictured: Neural (nervous system) stem cells grown in conditions that encourage them to mature into motor neurons. The c...”
     
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  • SMA - Ashlyn Spring, PhD
    Funded: 08/01/19 through 07/31/22
    Grant Announced: Summer 2019
    Disease Type: Spinal Muscular Atrophy (SMA)
    “Ashlyn Spring, PhD, a postdoctoral fellow in Biological and Genome Sciences at the University of North Carolina at Chape...”
     
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  • Charlotte Sumner, M.D.
    Funded: 09/01/22 through 08/31/25
    Grant Announced: 2022
    Disease Type: Spinal Muscular Atrophy (SMA)
     
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