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41 grants match your search

  • CMT - Charles Abrams, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “"This project will generate new understanding of how mutations in the gene for the connexin 32 protein lead to central n...”
     
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  • CMT - Charles Abrams, MD, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Unraveling the cause of a human disease requires having appropriate animal models for the disease being studied. This pr...”
     
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  • CMT - Anthony Antonellis, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Anthony Antonellis is studying how mutations in genes for certain enzymes lead abnormalities in CMT-affected cells. Char...”
     
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  • CMT - Elisabetta Babetto, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Elisabetta Babetto will study whether manipulating the PHR1 protein pathway helps to preserve nerve fibers in mice with ...”
     
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  • CMT - Robert Baloh, M.D., Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Within the fields of ALS and CMT research, Robert Baloh’s specific focus is on using human genetics as a guide toward ...”
     
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  • CMT — Bogdan Beirowski, M.D., Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Beirowski is studying the loss of axons in Charcot-Marie-Tooth disease (CMT). (Axons are the long fibers through which n...”
     
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  • CMT – Bogdan Karl Beirowski, MD, PhD
    Funded: 08/01/18 through 07/31/21
    Grant Announced: Summer 2018
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Axon degeneration is a central component of irreversible neurological disability in many neuromuscular diseases. There i...”
     
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  • CMT – Alessandra Bolino, PhD
    Funded: 08/01/18 through 07/31/21
    Grant Announced: Summer 2018
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Our research is aimed at unravelling how myelination is regulated in the PNS and how perturbation of these mechanisms ca...”
     
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  • CMT - Robert Burgess, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Robert Burgess is interested in developing mouse models of CMT and related neuromuscular disorders, and using these mice...”
     
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  • Establishing a network of highly trained and reliable CMT clinical evaluators – Joshua Burns, PhD
    Funded: 09/01/21 through 08/31/22
    Grant Announced: 2021
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Charcot-Marie-Tooth disease (CMT) is a genetic neuromuscular disease, causing muscle weakness, foot deformities, and fre...”
     
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  • CMT - Gavriel David, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Gavriel David is investigating calcium overload in CMT-affected nerve cells. Shown here is a mouse nerve fiber, with an ...”
     
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  • CMT - Aaron DiAntonio, M.D., Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Aaron DiAntonio is working to identify genetic suppressors of motor neuron axon degeneration that can then be evaluated ...”
     
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  • CMT - Gerald W. Dorn, II, MD
    Funded: 08/01/19 through 07/31/21
    Grant Announced: Summer 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “There is currently no disease-modifying treatment for CMT2A; mitofusin agonists may be the first. This is an orphan dise...”
     
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  • CMT - Vera Fridman, M.D.
    Grant Announced: Winter 2013
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “HSAN is a rare genetic neuropathy that causes severe numbness, weakness and ulceration of the feet and hands.”
     
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  • Machine Learning of Neuromuscular Disease Gait Parameters from Single Sensors - Erik Henricson, PhD
    Funded: 01/01/20 through 12/31/22
    Grant Announced: Summer 2020
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “The overall goal of this project is to develop new and innovative mobile device-compatible methodologies based on low-co...”
     
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  • CMT — Peter Hiesinger, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Partial loss of function of the rab7 protein causes slow adult-onset degeneration of individual fly photoreceptor cells,...”
     
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  • CMT - Henry Houlden, M.D., Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    ““My focus is on finding genes and disease pathways,” Henry Houlden says. “By identifying genes we can give patient...”
     
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  • CMT - Nivedita Jerath, M.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Nivedita Jerath is studying driving ability in people with type 1A CMT. Charcot-Marie-Tooth Disease (CMT)”
     
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  • CMT — Albena Jordanova
    Grant Announced: Summer 2010
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Images taken with a scanning electron microscope show (left) the eye of a fruit fly carrying the human YARS protein cont...”
     
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  • Kleopas Kleopa, M.D.
    Grant Announced: Winter 2017
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    ““All of the inherited neuropathies remain incurable despite the progress made in the last couple of decades in underst...”
     
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  • CMT - Kleopas Kleopa, MD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “By establishing an effective, clinically applicable gene therapy approach targeting peripheral nerves, we may be able to...”
     
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  • CMT — Kleopas Kleopa, M.D.
    Grant Announced: Summer 2013
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Viral delivery of the connexin 32 gene allows increased protein production (arrows) in the myelin sheath.”
     
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  • CMT - Ronald K. Liem, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Spinal cords from unaffected mice (left), and mice with a mutation in the NFL gene (right) are stained with anti-NFL ant...”
     
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  • CMT/FA — Jeffrey Milbrandt, M.D., Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Milbrandt and colleagues are studying neuropathy, a potentially debilitating condition caused by abnormal nerve function...”
     
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  • CMT/DSD - Kelly Monk, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Kelly Monk is studying the formation and maintenance of the myelin sheath, an insulating coating that surrounds many ner...”
     
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  • CMT - Thien Nguyen, M.D., Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Nguyen's lab has focused for more than five years on the prevention of axonal degeneration in demyelinating and dysmyeli...”
     
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  • CMT - Garth Nicholson, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Nicholson and colleagues are studying effects of mutations in the ATP7A gene, essential for human copper metabolism.”
     
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  • CMT, MM, other NMDs - Wolfgang Pernice, PhD
    Funded: 08/01/19 through 07/31/22
    Grant Announced: Summer 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Our research aims to develop unbiased experimental strategies and tools to systematically address critical roadblocks in...”
     
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  • CMT - Mary M. Reilly, M.D., FRCP, FRCPI
    Funded: 12/01/17 through 12/31/20
    Grant Announced: Additional Grants 2018
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    ““We are grateful to MDA for its support of this extremely important work,” Mary Reilly said. “The results from our...”
     
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  • CMT - Michael Shy, M.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Michael Shy plans to conduct a clinical trial of an experimental treatment in patients with CMT1B. Charcot-Marie-Tooth D...”
     
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  • CMT – Michael Shy, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Additional Grants 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Rational clinical trials in CMT with outcome measures that can measure effectiveness are in place and will hopefully lea...”
     
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  • CMT - Michael Shy, M.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Michael Shy plans to conduct a clinical trial of an experimental treatment in patients with CMT1B. Charcot-Marie-Tooth D...”
     
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  • Erik Storkebaum, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    ““The molecular mechanisms underlying Charcot-Marie-Tooth disease and ALS are poorly understood, and both diseases are ...”
     
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  • CMT - Daniel Summers, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Daniel Summers is working to identify new therapeutic avenues for prolonging nerve function and improving the quality of...”
     
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  • CMT, SMA - Charlotte Sumner, MD
    Funded: 08/01/19 through 07/31/22
    Grant Announced: Summer 2019
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Charlotte Sumner, MD, professor of Neurology and Neuroscience at Johns Hopkins University School of Medicine in Baltimor...”
     
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  • CMT — Charlotte Sumner, M.D.
    Grant Announced: Summer 2013
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “A mutation in the calcium channel TRPV4 causes CMT in humans and affects wing development in a fly model of the disease.”
     
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  • CMT – Vincent Timmerman, PhD
    Funded: 08/01/18 through 07/31/21
    Grant Announced: Summer 2018
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “If we can successfully validate our research hypothesis, reducing the expression of HSPB8 in vivo and decreasing the det...”
     
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  • CMT - Ludo Van Den Bosch, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Ludo Van Den Bosch is investigating the possible use of a compound known as an HDAC6 inhibitor in treating type 2F CMT a...”
     
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  • CMT — Stephan Züchner, M.D.
    Grant Announced: Summer 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    ““Our work will eventually help to better define the genetic basis of CMT, analyze multigenic effects, and use small bi...”
     
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  • CMT – Stephan Zuchner, M.D., Ph.D.
    Funded: 12/01/17 through 01/21/20
    Grant Announced: Winter 2018
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “An open Charcot-Marie-Tooth genetics data resource could help expedite CMT research, from gene identification to drug di...”
     
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  • Data Resource for CMT Genomics - Stephan Zuchner, MD, PhD
    Funded: 01/01/21 through 12/31/23
    Grant Announced: Summer 2020
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “An open Charcot-Marie-Tooth genetics data resource could help expedite CMT research, from gene identification to drug di...”
     
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