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Innovations in Science

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124 grants match your search

  • ALS — ALS Therapy Development Institute (ALS TDI)
    Grant Announced: Additional Grants 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
     
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  • ALS — Bridge-to-Industry Training Program
    Grant Announced: Additional Grants 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
     
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  • ALS — NeuRx Diaphragm Pacing System (DPS)
    Grant Announced: Additional Grants 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
     
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  • ALS — National Institutes of Health (NIH) Laboratory
    Grant Announced: Additional Grants 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
     
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  • ALS - Iron Horse Diagnostics
    Funded: 04/03/17 through 05/03/18
    Grant Announced: Additional Grants 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Our prognostic test will be an essential tool to enhance drug development for ALS,” said Iron Horse Diagnostics Chi...”
     
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  • ALS - Samuel Alworth, MS, MBA
    Funded: 10/23/18 through 10/31/20
    Grant Announced: Winter 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
     
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  • ALS - Stanley Appel, MD
    Funded: 07/01/18 through 12/30/20
    Grant Announced: Additional Grants 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Stanley Appel, MD, co-director of Houston Methodist Neurological Institute, chair of the Stanley H. Appel Department of ...”
     
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  • ALS — Stanley H. Appel
    Grant Announced: Summer 2010
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “"In ALS, neurons do not die alone," Appel said. Injury to, and death of, the cells results from "crosstalk" among certai...”
     
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  • ALS - Stanley Appel, M.D.
    Grant Announced: Spring 2014
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Stanley Appel is studying how the immune system behaves in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS - Gary Armstrong, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Gary Armstrong’s research focus is on the synaptic defects that occur in the spinal cord and at the neuromuscular junc...”
     
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  • ALS – Nazem Atassi, M.D., MSSc
    Funded: 12/01/17 through 11/30/19
    Grant Announced: Additional Grants 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “One of the main roadblocks for ALS drug development is the lack of markers that tell us about drug efficacy in patients,...”
     
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  • ALS - Paul August, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Paul August is using novel technology to develop a chip that will facilitate the testing of experimental therapies for A...”
     
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  • ALS - Ellen Barrett, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “These images show motor nerve terminals in the hind limb of a healthy mouse (left) and that of an ALS-affected mouse (ri...”
     
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  • ALS - Asim Beg, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““The devastating impact that ALS has on patients and their families is a major factor that has inspired me to study th...”
     
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  • ALS – Michael Benatar, M.D., Ph.D., and Jonathan Katz, M.D.
    Funded: 03/01/17 through 02/28/19
    Grant Announced: Additional Grants 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Integration of a mechanism to collect research-useful data through a clinical workflow within the electronic health r...”
     
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  • ALS — Michael Benatar
    Grant Announced: Summer 2010
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “"MDA funding has been absolutely critical for this study," Benatar said, noting that the "strength" of the study lies in...”
     
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  • ALS - James Berry, M.D.
    Grant Announced: Winter 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Berry and colleagues are planning a phase 2 human clinical trial of the experimental drug ISIS-333611 as a follow-on stu...”
     
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  • ALS - François Berthod, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “This image shows mouse nervous system cells cultured in a three-dimensional environment. Motor neurons (red) and Schwann...”
     
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  • ALS, CMT - Martha Bhattacharya, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “The peripheral nervous system of the fruit fly Drosophila melanogaster, shown with synaptic vesicle proteins in green an...”
     
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  • ALS - Antonius Bunt
    Funded: 01/01/17 through 07/01/18
    Grant Announced: Additional Grants 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “"This MDA grant is important for moving our IZ10023 platform technology forward, with potential benefits for not only pe...”
     
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  • ALS — Don Cleveland, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Cleveland expects his new studies to show “whether any benefit from increased mitochondrial activity is shared among m...”
     
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  • ALS - Don Cleveland, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Don Cleveland is working on development and testing of gene silencing therapies targeting genes that drive inherited or ...”
     
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  • ALS, IBM - Benoit Coulombe, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Benoit Coulombe (left) and key collaborators in this MDA project, Philippe Cloutier (center) and Denis Faubert (right), ...”
     
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  • ALS - Sandrine Da Cruz, PhD
    Funded: 08/01/19 through 07/31/22
    Grant Announced: Summer 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “This work will provide critical insight for elucidating the mechanisms regulating protein aggregation and cell-to-cell s...”
     
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  • ALS - Heather Durham, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “In this image of a motor neuron, the bright dots are clumps containing mutant FUS protein.”
     
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  • ALS – Heather Durham, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Heather Durham’s work focuses on the role of the nBAF protein complex in the health and activity of motor neurons (ner...”
     
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  • ALS - Jone Lopez Erauskin, PhD
    Funded: 08/01/19 through 07/31/22
    Grant Announced: Summer 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “I expect to determine how stathmin-2 provides a crucial role in the maintenance and regeneration of the neuromuscular ju...”
     
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  • ALS - Mohamed Farah, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““The overall goal of this grant is to investigate whether the capacity of motor nerves to regenerate after insult or d...”
     
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  • Mohamed Farah, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Without this grant and previous funding from MDA, we would not have been able to work on motor neuron disease,” Moh...”
     
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  • ALS — Brian Freibaum
    Grant Announced: Summer 2010
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Freibaum will use fruit fly and mouse models, as well as cultured human cell lines, in his three-tiered approach to dete...”
     
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  • ALS - Thomas Gaj, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “We’re in the middle of a scientific revolution that’s seeing the development of increasingly precise and effective t...”
     
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  • Fen-Biao Gao, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Research in the C9ORF72 ALS field is moving forward rapidly,” Fen-Biao Gao says. “We are hopeful that collective ...”
     
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  • ALS – Fatima Gasset-Rosa, Ph.D.
    Funded: 02/01/18 through 01/31/18
    Grant Announced: Winter 2018
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “I believe that understanding the initial event that provokes TDP-43 abnormalities and TDP-43 spread within the nervous s...”
     
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  • ALS – Tania Gendron, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Tremendous progress has been made towards deciphering the underlying causes of ALS, and the recent discovery of the C...”
     
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  • ALS - Tania Gendron, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “We hope that the biomarkers of cognitive impairment identified through this work will prove useful in the clinical asses...”
     
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  • ALS - Aaron Gitler, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Aaron Gitler is investigating how profilin 1 gene mutations cause ALS, with the hope that understanding this phenomenon ...”
     
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  • ALS - Jonathan Glass, MD
    Funded: 11/01/18 through 10/31/21
    Grant Announced: Winter 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Research into ALS cannot move forward without the participation of patients, who provide the needed clinical information...”
     
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  • ALS — Raymond Grill, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “"The study of ALS is a new focus for my laboratory," Grill said. "In fact, the idea tested in this MDA-funded proposal a...”
     
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  • ALS - Maurizio Grimaldi, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Maurizio Grimaldi is developing new molecules that may protect nerve cells in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS - Junjie Guo, PhD
    Funded: 02/01/19 through 01/31/22
    Grant Announced: Winter 2019
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “The pathophysiological mechanisms underlying ALS and other neuromuscular diseases are still poorly understood. Only thro...”
     
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  • ALS - Amanda Haidet-Phillips, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Amanda Haidet-Phillips is investigating how upper motor neurons are lost in ALS. Here, upper motor neurons are shown in ...”
     
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  • Muscle Physiology — Samantha Harris, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Shown in green is myosin binding protein C. The red bands indicate another protein, called myomesin. Each green and red ...”
     
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  • ALS - Muralidhar Hegde, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Muralidhar Hegde is studying whether inadequate DNA repair by a protein called TDP43 is involved in causing ALS. Amyotro...”
     
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  • ALS - Terry Heiman-Patterson, M.D.
    Grant Announced: Winter 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “The identification of "modifier genes," which can affect the severity of diseases including ALS, will highlight intracel...”
     
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  • ALS - Kenneth Hensley, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Favorable results from Hensley’s new project could lead to the creation of one or more investigational new drug (IND) ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “"Due to the fact that most ALS cases are considered sporadic [noninherited] with no clear genetic component, we believe ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    ““Patients afflicted with ALS now need to know that we are working for them, even though our current scientific efforts...”
     
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  • ALS — Oliver Hobert
    Grant Announced: Summer 2010
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Nerve cells called motor neurons in the spinal cord of the nematode (roundworm) C. elegans are labeled with red fluoresc...”
     
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  • ALS - Fenghua Hu, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Mutant TDP43 fragments readily form aggregates (green) in mammalian cells, which are occasionally surrounded by the ubiq...”
     
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  • ALS - Eric Huang, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Amyotrophic Lateral Sclerosis (ALS)
    “Left: Staining in the spinal cord of a normal (control) mouse model shows elaborate motor neuron structure. Right: In co...”
     
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