Hope Through Research

At MDA, we take a big picture perspective across the full spectrum of neuromuscular diseases to uncover scientific and medical breakthroughs that accelerate treatments and cures. The power in our research approach is that we can often apply learnings from one disease to progress in others to bring urgently-needed answers to our families.

465 grants match your search

  • ALS - François Berthod, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “This image shows mouse nervous system cells cultured in a three-dimensional environment. Motor neurons (red) and Schwann...”
     
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  • DMD/BMD — Carmen Bertoni
    Grant Announced: Summer 2010
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Under the microscope: Cross sections of muscle analyzed for dystrophin, the protein missing but needed in Duchenne muscu...”
     
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  • DMD — Carmen Bertoni, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Carmen Bertoni, Ph.D., focuses on studying gene-editing strategies for DMD.”
     
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  • ALS, CMT - Martha Bhattacharya, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “The peripheral nervous system of the fruit fly Drosophila melanogaster, shown with synaptic vesicle proteins in green an...”
     
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  • FA - Sanjay Bidichandani, M.B.B.S., Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Friedreich's Ataxia (FA)
    ““We believe that this project will enhance our understanding of the molecular pathogenesis of Friedreich’s ataxia, a...”
     
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  • DD/LGMD - Robert Bloch, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Distal Myopathies
    “As part of their research, Bloch and colleagues will test shortened versions of the dysferlin protein for use in gene th...”
     
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  • FSHD — Gregory Block, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Facioscapulohumeral Muscular Dystrophy (FSH, FSHD)
    “Cells taken from an FSHD patient were coaxed to become early-stage muscle fibers called myotubes. The cells are labeled ...”
     
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  • Nemaline Myopathy – Jordan Blondelle, Ph.D.
    Funded: 08/01/17 through 07/31/20
    Grant Announced: Summer 2017
    Disease Type: Endocrine Myopathies
    “My focus is to better understand the role that Cullin-3-related protein degradation may play in the pathological mechani...”
     
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  • DMD/BMD - Andrew Brack, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Brack studies adult muscle stem cells called "satellite cells," and seeks to determine what role, if any, this type of c...”
     
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  • CMS — Paul Brehm, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Congenital Myasthenic Syndromes (CMS)
    “Brehm and Dr. Mike Linhoff at their array tomography setup, where they are generating high-resolution images of the zebr...”
     
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  • ALS - Antonius Bunt
    Funded: 01/01/17 through 07/01/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"This MDA grant is important for moving our IZ10023 platform technology forward, with potential benefits for not only pe...”
     
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  • CMT - Robert Burgess, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Robert Burgess is interested in developing mouse models of CMT and related neuromuscular disorders, and using these mice...”
     
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  • SMA - Arthur Burghes, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Spinal Muscular Atrophy
    “Arthur Burghes is working to develop a new technique that will allow scientists to accurately predict the severity of a ...”
     
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  • DMD/BMD — Dean Burkin, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Burkin is working to test the hypothesis that laminin-111 protein therapy can prevent muscle damage after disease onset ...”
     
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  • DMD – Dean Burkin, Ph.D.
    Funded: 08/01/17 through 07/31/20
    Grant Announced: Summer 2017
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “I have received other MDA grants which have been critical to these studies,” Dean Burkin says. “This new grant will ...”
     
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  • LGMD – Michele Calos, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Limb-Girdle Muscular Dystrophy (LGMD)
    ““We are inspired to study LGMD2B and 2D because we are working with families who have patients with these disorders,...”
     
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  • DMD/BMD — Michele Calos
    Grant Announced: Summer 2010
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Pictured: cross-section of a normal mouse leg muscle that has been stained for dystrophin, the protein missing in Duchen...”
     
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  • CMD — Kevin Campbell, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Congenital Muscular Dystrophy (CMD)
    “Longtime MDA grantee Kevin Campbell says current research aims to identify proteins that contribute to the initiation of...”
     
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  • Periodic Paralysis — Stephen Cannon, M.D., Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Endocrine Myopathies
    ““With years of support,” Cannon said, “our MDA-sponsored work progressed from establishing the functional abnormal...”
     
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  • periodic paralysis - Steve Cannon, M.D., Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Endocrine Myopathies
    “Steve Cannon is investigating the mechanistic basis for exercise-induced weakness in periodic paralysis.”
     
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  • FSHD – Joel Chamberlain, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Facioscapulohumeral Muscular Dystrophy (FSH, FSHD)
    ““Our area of focus is important in achieving a greater understanding of the early changes in muscle resulting from DUX...”
     
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  • DMD/BMD — Jeffrey Chamberlain, Ph.D.
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • FSHD — Joel Chamberlain, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Facioscapulohumeral Muscular Dystrophy (FSH, FSHD)
    “Many years of research have led recently to an understanding of the unique series of molecular events necessary to cause...”
     
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  • MM - David Chan, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Mitochondrial Myopathies (MM)
    “David Chan will study defects in the behavior of mitochondria, which produce energy in cells, in mice with mitochondrial...”
     
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  • Vijayendran Chandran, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: Friedreich's Ataxia (FA)
    ““Molecular biomarkers are important tools in assessing clinical trial outcomes, measuring disease progression, and eva...”
     
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  • DMD — Tathagata Chaudhuri, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Adult human stem cells derived from bone marrow are called mesenchymal stem cells, or MSCs. Those pictured above have be...”
     
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  • Muscle Physiology - Elizabeth Chen, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Congenital Muscular Dystrophy (CMD)
    “Pictured: An immature muscle cell called a myoblast (pseudo-colored in pink) invades a myotube (an aggregation of myobla...”
     
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  • MMD — Ju Chen
    Grant Announced: Summer 2010
    Disease Type: Myotonic Dystrophy (DM)
    “Voluntary (skeletal) muscle at 100 times magnification.”
     
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  • DMD/BMD — Martin Childers, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Childers and colleagues will derive dystrophin-deficient heart cells from the skin cells of people with Duchenne MD, and...”
     
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  • MG - Premkumar Christadoss, M.B.B.S.
    Grant Announced: Winter 2012
    Disease Type: Myasthenia Gravis (MG)
    “Christadoss is working to find a specific therapy for myasthenia gravis that can induce long-term remission of the disea...”
     
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  • CMD, LGMD - Sebahattin Cirak, M.D.
    Grant Announced: Winter 2013
    Disease Type: Congenital Muscular Dystrophy (CMD)
    “Using the latest sequencing technology, Cirak will study RNA extracted from muscle biopsies of people with CMD or LGMD t...”
     
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  • ALS — Don Cleveland, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Cleveland expects his new studies to show “whether any benefit from increased mitochondrial activity is shared among m...”
     
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  • ALS - Don Cleveland, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Don Cleveland is working on development and testing of gene silencing therapies targeting genes that drive inherited or ...”
     
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  • DMD — Anne Connolly, M.D.
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Anne Connolly, M.D.”
     
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  • MMD — Thomas Cooper, M.D.
    Grant Announced: Summer 2013
    Disease Type: Myotonic Dystrophy (DM)
    “Mutant accumulated RNA (green) located within nuclei (blue) of heart tissue of a mouse model for type 1 myotonic dystrop...”
     
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  • FA - Giovanni Coppola, M.D.
    Grant Announced: Winter 2011
    Disease Type: Friedreich's Ataxia (FA)
    “Because there are numerous compounds with therapeutic potential for Friedreich's ataxia at the preclinical stage of deve...”
     
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  • OPMD – Anita Corbett, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Oculopharyngeal Muscular Dystrophy (OPMD)
    ““My specific expertise in the biological area impacted in OPMD was my initial inspiration to study the disease, but no...”
     
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  • DMD/BMD — Dawn Cornelison
    Grant Announced: Summer 2010
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “"My lab works to understand how satellite cells, the stem cells of skeletal muscle, act to efficiently and reproducibly ...”
     
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  • SBMA/ALS — Constanza Cortes, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Spinal-Bulbar Muscular Atrophy (SBMA)
    “Constanza Cortes will study regulators of a cell recycling system that is disrupted in SBMA and ALS.”
     
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  • Manuela Corti, Ph.D.
    Funded: 02/01/17 through 01/31/20
    Grant Announced: Winter 2017
    Disease Type: Friedreich's Ataxia (FA)
    “Manuela Corti aims to optimize gene therapy approaches for replacing frataxin in a mouse model of Friedreich’s ataxia,...”
     
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  • Mitochondrial Myopathy, DMD – Gino Cortopassi, Ph.D.
    Funded: 08/01/17 through 07/31/20
    Grant Announced: Summer 2017
    Disease Type: Mitochondrial Myopathies (MM)
    “We believe that this drug, already approved for use in humans, will cure mitochondrial disease in animals,” Gino Corto...”
     
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  • ALS, IBM - Benoit Coulombe, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Benoit Coulombe (left) and key collaborators in this MDA project, Philippe Cloutier (center) and Denis Faubert (right), ...”
     
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  • LGMD — Richard Cripps
    Grant Announced: Summer 2010
    Disease Type: Limb-Girdle Muscular Dystrophy (LGMD)
    “In completed studies, Cripps and colleagues observed that fruit flies with flawed Trim32 genes exhibit muscle degenerati...”
     
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  • Muscle disease - Colin Crist, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Spinal-Bulbar Muscular Atrophy (SBMA)
    “Applications of Colin Crist’s research include development of stem cell based treatments and discovery of modifiers of...”
     
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  • DMD — Rachelle Crosbie-Watson, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Rachelle Crosbie-Watson will test the feasibility of using gene transfer therapy to deliver the gene for the sarcospan p...”
     
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  • DMD, LGMD, CMD – Rachelle Crosbie-Watson, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    ““For the first time, there are numerous ongoing clinical trials focused on Duchenne muscular dystrophy,” Rachelle Cr...”
     
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  • DMD/BMD — Peter Currie, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Currie and colleagues will test molecules with possible therapeutic relevance for Duchenne or Becker muscular dystrophy ...”
     
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  • CMD - Peter Currie, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Congenital Muscular Dystrophy (CMD)
    “Peter Currie is conducting small molecule screening in live zebrafish larvae to isolate small molecules that can modulat...”
     
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  • DMD, General MD - Radbod Darabi, M.D., Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “The development of induced pluripotent stem cells “opens a new window of opportunity to use patient-specific pluripote...”
     
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  • CMT - Gavriel David, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Gavriel David is investigating calcium overload in CMT-affected nerve cells. Shown here is a mouse nerve fiber, with an ...”
     
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