Hope Through Research

At MDA, we take a big picture perspective across the full spectrum of neuromuscular diseases to uncover scientific and medical breakthroughs that accelerate treatments and cures. The power in our research approach is that we can often apply learnings from one disease to progress in others to bring urgently-needed answers to our families.

101 grants match your search

  • ALS — ALS Therapy Development Institute (ALS TDI)
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — Bridge-to-Industry Training Program
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — NeuRx Diaphragm Pacing System (DPS)
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — National Institutes of Health (NIH) Laboratory
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS - Iron Horse Diagnostics
    Funded: 04/03/17 through 05/03/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Our prognostic test will be an essential tool to enhance drug development for ALS,” said Iron Horse Diagnostics Chi...”
     
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  • ALS - Stanley Appel, M.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Stanley Appel is studying how the immune system behaves in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS — Stanley H. Appel
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"In ALS, neurons do not die alone," Appel said. Injury to, and death of, the cells results from "crosstalk" among certai...”
     
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  • ALS - Gary Armstrong, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Gary Armstrong’s research focus is on the synaptic defects that occur in the spinal cord and at the neuromuscular junc...”
     
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  • ALS – Nazem Atassi, M.D., MSSc
    Funded: 12/01/17 through 11/30/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “One of the main roadblocks for ALS drug development is the lack of markers that tell us about drug efficacy in patients,...”
     
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  • ALS - Paul August, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Paul August is using novel technology to develop a chip that will facilitate the testing of experimental therapies for A...”
     
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  • ALS - Ellen Barrett, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “These images show motor nerve terminals in the hind limb of a healthy mouse (left) and that of an ALS-affected mouse (ri...”
     
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  • ALS - Asim Beg, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The devastating impact that ALS has on patients and their families is a major factor that has inspired me to study th...”
     
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  • ALS — Michael Benatar
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"MDA funding has been absolutely critical for this study," Benatar said, noting that the "strength" of the study lies in...”
     
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  • ALS – Michael Benatar, M.D., Ph.D., and Jonathan Katz, M.D.
    Funded: 03/01/17 through 02/28/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Integration of a mechanism to collect research-useful data through a clinical workflow within the electronic health r...”
     
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  • ALS - James Berry, M.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Berry and colleagues are planning a phase 2 human clinical trial of the experimental drug ISIS-333611 as a follow-on stu...”
     
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  • ALS - François Berthod, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “This image shows mouse nervous system cells cultured in a three-dimensional environment. Motor neurons (red) and Schwann...”
     
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  • ALS, CMT - Martha Bhattacharya, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “The peripheral nervous system of the fruit fly Drosophila melanogaster, shown with synaptic vesicle proteins in green an...”
     
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  • ALS - Antonius Bunt
    Funded: 01/01/17 through 07/01/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"This MDA grant is important for moving our IZ10023 platform technology forward, with potential benefits for not only pe...”
     
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  • ALS - Don Cleveland, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Don Cleveland is working on development and testing of gene silencing therapies targeting genes that drive inherited or ...”
     
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  • ALS — Don Cleveland, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Cleveland expects his new studies to show “whether any benefit from increased mitochondrial activity is shared among m...”
     
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  • ALS, IBM - Benoit Coulombe, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Benoit Coulombe (left) and key collaborators in this MDA project, Philippe Cloutier (center) and Denis Faubert (right), ...”
     
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  • ALS - Heather Durham, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “In this image of a motor neuron, the bright dots are clumps containing mutant FUS protein.”
     
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  • ALS – Heather Durham, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Heather Durham’s work focuses on the role of the nBAF protein complex in the health and activity of motor neurons (ner...”
     
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  • ALS - Mohamed Farah, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The overall goal of this grant is to investigate whether the capacity of motor nerves to regenerate after insult or d...”
     
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  • Mohamed Farah, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Without this grant and previous funding from MDA, we would not have been able to work on motor neuron disease,” Moh...”
     
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  • ALS — Brian Freibaum
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Freibaum will use fruit fly and mouse models, as well as cultured human cell lines, in his three-tiered approach to dete...”
     
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  • Fen-Biao Gao, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Research in the C9ORF72 ALS field is moving forward rapidly,” Fen-Biao Gao says. “We are hopeful that collective ...”
     
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  • ALS – Fatima Gasset-Rosa, Ph.D.
    Funded: 02/01/18 through 01/31/18
    Grant Announced: Winter 2018
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “I believe that understanding the initial event that provokes TDP-43 abnormalities and TDP-43 spread within the nervous s...”
     
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  • ALS – Tania Gendron, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Tremendous progress has been made towards deciphering the underlying causes of ALS, and the recent discovery of the C...”
     
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  • ALS - Aaron Gitler, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Aaron Gitler is investigating how profilin 1 gene mutations cause ALS, with the hope that understanding this phenomenon ...”
     
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  • ALS — Raymond Grill, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"The study of ALS is a new focus for my laboratory," Grill said. "In fact, the idea tested in this MDA-funded proposal a...”
     
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  • ALS - Maurizio Grimaldi, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Maurizio Grimaldi is developing new molecules that may protect nerve cells in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS - Amanda Haidet-Phillips, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Amanda Haidet-Phillips is investigating how upper motor neurons are lost in ALS. Here, upper motor neurons are shown in ...”
     
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  • Muscle Physiology — Samantha Harris, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Shown in green is myosin binding protein C. The red bands indicate another protein, called myomesin. Each green and red ...”
     
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  • ALS - Muralidhar Hegde, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Muralidhar Hegde is studying whether inadequate DNA repair by a protein called TDP43 is involved in causing ALS. Amyotro...”
     
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  • ALS - Terry Heiman-Patterson, M.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “The identification of "modifier genes," which can affect the severity of diseases including ALS, will highlight intracel...”
     
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  • ALS - Kenneth Hensley, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Favorable results from Hensley’s new project could lead to the creation of one or more investigational new drug (IND) ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"Due to the fact that most ALS cases are considered sporadic [noninherited] with no clear genetic component, we believe ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Patients afflicted with ALS now need to know that we are working for them, even though our current scientific efforts...”
     
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  • ALS — Oliver Hobert
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Nerve cells called motor neurons in the spinal cord of the nematode (roundworm) C. elegans are labeled with red fluoresc...”
     
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  • ALS - Fenghua Hu, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Mutant TDP43 fragments readily form aggregates (green) in mammalian cells, which are occasionally surrounded by the ubiq...”
     
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  • ALS - Eric Huang, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Left: Staining in the spinal cord of a normal (control) mouse model shows elaborate motor neuron structure. Right: In co...”
     
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  • ALS - Justin Ichida, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Using nerve cells generated through cellular reprogramming of patient skin and blood samples, Justin Ichida will work to...”
     
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  • ALS - Adrian Israelson, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Studies have shown, in spinal cords from the SOD1G37R research mouse model, that there is little accumulation of misfold...”
     
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  • ALS — Dena Jacob
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"I'm honored and excited to be a recipient of an MDA Development Grant," Jacob said. "And I look forward to working with...”
     
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  • ALS — Vasanthi Jayaraman, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““This illustration depicts the structure of the agonist binding domain of the AMPA receptor with attached fluorophores...”
     
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  • Jie Jiang, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"ALS is one of the most devastating diseases I have ever seen,” Jie Jiang says. “Sadly, no medication is available t...”
     
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  • ALS — Jean-Pierre Julien
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Julien and colleagues aim to determine how a genetic variant called P413L in the chromogranin B protein increases suscep...”
     
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  • ALS - Nam Chul Kim, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Nam Chul Kim’s work could have impact in a number of diseases including amyotrophic lateral sclerosis (ALS), frontotem...”
     
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  • ALS, IBM - Hong Joo Kim, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““We seek to recapitulate the full spectrum of MSP, to elucidate the molecular mechanism of pathogenesis, and to identi...”
     
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