Innovations in Science

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110 grants match your search

  • ALS — ALS Therapy Development Institute (ALS TDI)
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — Bridge-to-Industry Training Program
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — NeuRx Diaphragm Pacing System (DPS)
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — National Institutes of Health (NIH) Laboratory
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS - Iron Horse Diagnostics
    Funded: 04/03/17 through 05/03/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Our prognostic test will be an essential tool to enhance drug development for ALS,” said Iron Horse Diagnostics Chi...”
     
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  • ALS — Stanley H. Appel
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"In ALS, neurons do not die alone," Appel said. Injury to, and death of, the cells results from "crosstalk" among certai...”
     
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  • ALS - Stanley Appel, M.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Stanley Appel is studying how the immune system behaves in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS - Gary Armstrong, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Gary Armstrong’s research focus is on the synaptic defects that occur in the spinal cord and at the neuromuscular junc...”
     
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  • ALS – Nazem Atassi, M.D., MSSc
    Funded: 12/01/17 through 11/30/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “One of the main roadblocks for ALS drug development is the lack of markers that tell us about drug efficacy in patients,...”
     
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  • ALS - Paul August, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Paul August is using novel technology to develop a chip that will facilitate the testing of experimental therapies for A...”
     
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  • ALS - Ellen Barrett, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “These images show motor nerve terminals in the hind limb of a healthy mouse (left) and that of an ALS-affected mouse (ri...”
     
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  • ALS - Asim Beg, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The devastating impact that ALS has on patients and their families is a major factor that has inspired me to study th...”
     
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  • ALS — Michael Benatar
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"MDA funding has been absolutely critical for this study," Benatar said, noting that the "strength" of the study lies in...”
     
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  • ALS – Michael Benatar, M.D., Ph.D., and Jonathan Katz, M.D.
    Funded: 03/01/17 through 02/28/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Integration of a mechanism to collect research-useful data through a clinical workflow within the electronic health r...”
     
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  • ALS - James Berry, M.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Berry and colleagues are planning a phase 2 human clinical trial of the experimental drug ISIS-333611 as a follow-on stu...”
     
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  • ALS - François Berthod, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “This image shows mouse nervous system cells cultured in a three-dimensional environment. Motor neurons (red) and Schwann...”
     
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  • ALS, CMT - Martha Bhattacharya, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “The peripheral nervous system of the fruit fly Drosophila melanogaster, shown with synaptic vesicle proteins in green an...”
     
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  • ALS - Antonius Bunt
    Funded: 01/01/17 through 07/01/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"This MDA grant is important for moving our IZ10023 platform technology forward, with potential benefits for not only pe...”
     
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  • ALS - Don Cleveland, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Don Cleveland is working on development and testing of gene silencing therapies targeting genes that drive inherited or ...”
     
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  • ALS — Don Cleveland, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Cleveland expects his new studies to show “whether any benefit from increased mitochondrial activity is shared among m...”
     
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  • ALS – Todd J. Cohen, PhD
    Funded: 08/01/18 through 07/31/21
    Grant Announced: Summer 2018
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “It surprises me that we don’t have better drugs to treat ALS patients. I think we need better models of ALS to test wh...”
     
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  • ALS, IBM - Benoit Coulombe, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Benoit Coulombe (left) and key collaborators in this MDA project, Philippe Cloutier (center) and Denis Faubert (right), ...”
     
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  • ALS – Heather Durham, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Heather Durham’s work focuses on the role of the nBAF protein complex in the health and activity of motor neurons (ner...”
     
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  • ALS - Heather Durham, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “In this image of a motor neuron, the bright dots are clumps containing mutant FUS protein.”
     
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  • ALS - Mohamed Farah, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The overall goal of this grant is to investigate whether the capacity of motor nerves to regenerate after insult or d...”
     
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  • Mohamed Farah, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Without this grant and previous funding from MDA, we would not have been able to work on motor neuron disease,” Moh...”
     
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  • ALS — Brian Freibaum
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Freibaum will use fruit fly and mouse models, as well as cultured human cell lines, in his three-tiered approach to dete...”
     
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  • Fen-Biao Gao, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Research in the C9ORF72 ALS field is moving forward rapidly,” Fen-Biao Gao says. “We are hopeful that collective ...”
     
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  • ALS – Fatima Gasset-Rosa, Ph.D.
    Funded: 02/01/18 through 01/31/18
    Grant Announced: Winter 2018
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “I believe that understanding the initial event that provokes TDP-43 abnormalities and TDP-43 spread within the nervous s...”
     
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  • ALS – Tania Gendron, Ph.D.
    Grant Announced: Summer 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Tremendous progress has been made towards deciphering the underlying causes of ALS, and the recent discovery of the C...”
     
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  • ALS - Aaron Gitler, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Aaron Gitler is investigating how profilin 1 gene mutations cause ALS, with the hope that understanding this phenomenon ...”
     
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  • ALS — Raymond Grill, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"The study of ALS is a new focus for my laboratory," Grill said. "In fact, the idea tested in this MDA-funded proposal a...”
     
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  • ALS - Maurizio Grimaldi, M.D., Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Maurizio Grimaldi is developing new molecules that may protect nerve cells in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS - Amanda Haidet-Phillips, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Amanda Haidet-Phillips is investigating how upper motor neurons are lost in ALS. Here, upper motor neurons are shown in ...”
     
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  • Muscle Physiology — Samantha Harris, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Shown in green is myosin binding protein C. The red bands indicate another protein, called myomesin. Each green and red ...”
     
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  • ALS - Muralidhar Hegde, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Muralidhar Hegde is studying whether inadequate DNA repair by a protein called TDP43 is involved in causing ALS. Amyotro...”
     
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  • ALS - Terry Heiman-Patterson, M.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “The identification of "modifier genes," which can affect the severity of diseases including ALS, will highlight intracel...”
     
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  • ALS - Kenneth Hensley, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Favorable results from Hensley’s new project could lead to the creation of one or more investigational new drug (IND) ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"Due to the fact that most ALS cases are considered sporadic [noninherited] with no clear genetic component, we believe ...”
     
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  • ALS - Claudio Hetz, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Patients afflicted with ALS now need to know that we are working for them, even though our current scientific efforts...”
     
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  • ALS — Oliver Hobert
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Nerve cells called motor neurons in the spinal cord of the nematode (roundworm) C. elegans are labeled with red fluoresc...”
     
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  • ALS - Fenghua Hu, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Mutant TDP43 fragments readily form aggregates (green) in mammalian cells, which are occasionally surrounded by the ubiq...”
     
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  • ALS - Eric Huang, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Left: Staining in the spinal cord of a normal (control) mouse model shows elaborate motor neuron structure. Right: In co...”
     
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  • ALS - Justin Ichida, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Using nerve cells generated through cellular reprogramming of patient skin and blood samples, Justin Ichida will work to...”
     
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  • ALS - Adrian Israelson, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Studies have shown, in spinal cords from the SOD1G37R research mouse model, that there is little accumulation of misfold...”
     
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  • ALS — Dena Jacob
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"I'm honored and excited to be a recipient of an MDA Development Grant," Jacob said. "And I look forward to working with...”
     
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  • ALS — Vasanthi Jayaraman, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““This illustration depicts the structure of the agonist binding domain of the AMPA receptor with attached fluorophores...”
     
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  • Jie Jiang, Ph.D.
    Grant Announced: Winter 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"ALS is one of the most devastating diseases I have ever seen,” Jie Jiang says. “Sadly, no medication is available t...”
     
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  • ALS — Jean-Pierre Julien
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Julien and colleagues aim to determine how a genetic variant called P413L in the chromogranin B protein increases suscep...”
     
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  • ALS, IBM - Hong Joo Kim, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““We seek to recapitulate the full spectrum of MSP, to elucidate the molecular mechanism of pathogenesis, and to identi...”
     
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