Innovations in Science

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482 grants match your search

  • MTM — Valerion Therapeutics
    Grant Announced: Additional Grants 2013
    Disease Type: Endocrine Myopathies
     
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  • DMD — Catabasis Pharmaceuticals
    Grant Announced: Additional Grants 2012
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Favorable results in mouse studies could lead to clinical trials for CAT-1004 or CAT-1040 in people with DMD.”
     
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  • ALS — National Institutes of Health (NIH) Laboratory
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS - Iron Horse Diagnostics
    Funded: 04/03/17 through 05/03/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Our prognostic test will be an essential tool to enhance drug development for ALS,” said Iron Horse Diagnostics Chi...”
     
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  • DMD — ReveraGen BioPharma
    Grant Announced: Additional Grants 2012
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • DMD — Halo Therapeutics
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • ALS — ALS Therapy Development Institute (ALS TDI)
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • DMD/BMD — Tivorsan Pharmaceuticals
    Grant Announced: Additional Grants 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
     
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  • DMD/BMD — ARMGO Pharma
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • ALS — Bridge-to-Industry Training Program
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — NeuRx Diaphragm Pacing System (DPS)
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • CMT - Charles Abrams, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “"This project will generate new understanding of how mutations in the gene for the connexin 32 protein lead to central n...”
     
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  • DMD - Matthew Alexander, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Alexander uses a variety of techniques, including the western gel film blot shown here, to identify expression of miR-48...”
     
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  • DMD – Matthew Alexander, Ph.D.
    Funded: 02/01/18 through 01/31/21
    Grant Announced: Winter 2018
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Many drugs for neuromuscular diseases fail to win FDA approval, resulting in a large amount of wasted time and resources...”
     
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  • CMD - Douglas Anderson, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Congenital Muscular Dystrophy (CMD)
    ““The continued discovery and characterization of key regulators of skeletal muscle function, such as myoregulin, will ...”
     
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  • CMT - Anthony Antonellis, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Anthony Antonellis is studying how mutations in genes for certain enzymes lead abnormalities in CMT-affected cells. Char...”
     
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  • ALS - Stanley Appel, M.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Stanley Appel is studying how the immune system behaves in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS — Stanley H. Appel
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"In ALS, neurons do not die alone," Appel said. Injury to, and death of, the cells results from "crosstalk" among certai...”
     
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  • DMD/BMD — Zolt Arany
    Grant Announced: Summer 2010
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “"MDA has had an important impact on research in muscular dystrophy," Zolt said. "Without MDA support, we would not be ab...”
     
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  • ALS - Gary Armstrong, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Gary Armstrong’s research focus is on the synaptic defects that occur in the spinal cord and at the neuromuscular junc...”
     
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  • DMD/BMD — Atsushi Asakura, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Asakura uses an inverted microscope to capture images of satellite cells, which play essential roles in muscle regenerat...”
     
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  • ALS – Nazem Atassi, M.D., MSSc
    Funded: 12/01/17 through 11/30/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “One of the main roadblocks for ALS drug development is the lack of markers that tell us about drug efficacy in patients,...”
     
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  • LEMS - William Atchison, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Lambert-Eaton Myasthenic Syndrome (LEMS)
    “Using a mouse model of LEMS, Atchison will explore the means by which certain types of calcium channel proteins are recr...”
     
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  • ALS - Paul August, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Paul August is using novel technology to develop a chip that will facilitate the testing of experimental therapies for A...”
     
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  • SMA - Tomoyuki Awano, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Spinal Muscular Atrophy
    “Using a confocal microscope, Awano views a neuromuscular junction in a mouse gastrocnemius muscle. On the computer monit...”
     
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  • CMT - Elisabetta Babetto, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Elisabetta Babetto will study whether manipulating the PHR1 protein pathway helps to preserve nerve fibers in mice with ...”
     
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  • Muscle disease - Mariah Baker, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Mariah Baker will investigate how calcium is released in muscle cells, which may lead to treatment for a variety of diso...”
     
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  • Pompe - Celine Baligand, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Metabolic Myopathies
    “The pre-clinical optimization of new potential treatments and the evaluation of their efficacy and administration routes...”
     
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  • CMT - Robert Baloh, M.D., Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Within the fields of ALS and CMT research, Robert Baloh’s specific focus is on using human genetics as a guide toward ...”
     
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  • OPMD - Ayan Banerjee, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Oculopharyngeal Muscular Dystrophy (OPMD)
    “Banerjee’s goal is to better understand how the PABN1 protein is regulated, in order to develop a better understanding...”
     
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  • ALS - Ellen Barrett, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “These images show motor nerve terminals in the hind limb of a healthy mouse (left) and that of an ALS-affected mouse (ri...”
     
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  • MM - Antoni Barrientos, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Mitochondrial Myopathies (MM)
    ““The study of mitochondria is now a very ‘hot issue’ for both basic and clinical research, Antoni Barrientos says....”
     
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  • Mito. Myopathy - Antoni Barrientos, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Mitochondrial Myopathies (MM)
    “Barrientos, pictured with collaborators Flavia Fontanesi and Jingjing Liu, notes that defects in an enzyme called cytoch...”
     
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  • SMA - Gary Bassell, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Spinal Muscular Atrophy
    ““Our central hypothesis is that SMN protein plays a critical role in facilitating regulation of mRNA transport in moto...”
     
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  • BMD, DMD - Linda Baum, M.D., Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Becker Muscular Dystrophy (BMD)
    ““By using these human muscle cells to screen drug libraries to identify compounds that improve cell function, our aim ...”
     
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  • SMA — Lisa Baumbach, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Spinal Muscular Atrophy
    “Baumbach (front, right) with the other members of the lab team that discovered the X-linked gene for spinal muscular atr...”
     
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  • EDMD — Mary Baylies, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Emery-Dreifuss Muscular Dystrophy (EDMD)
    “Like human muscle fibers, each fiber in a fruit fly (drosophila) is multinucleated and has a distinct size and shape. Un...”
     
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  • CCD — Kurt Beam, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Endocrine Myopathies
    “Beam uses electrical equipment to measure currents, and a confocal microscope to measure calcium inside cells.”
     
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  • PP — Kurt Beam
    Grant Announced: Summer 2010
    Disease Type: Endocrine Myopathies
    “"Our MDA research project, 'voltage sensor for excitation-contraction coupling,' seeks to understand how skeletal muscle...”
     
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  • DMD, BMD - Joseph Beavo, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Recent work from Beavo and others strongly suggests that sildenafil ameliorates much of the dysfunction seen in older md...”
     
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  • Aaron Beedle, Ph.D.
    Funded: 02/01/17 through 01/31/20
    Grant Announced: Winter 2017
    Disease Type: Limb-Girdle Muscular Dystrophy (LGMD)
    “Aaron Beedle and colleagues are working to determine whether drugs that target a common intracellular pathway for cell g...”
     
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  • ALS - Asim Beg, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The devastating impact that ALS has on patients and their families is a major factor that has inspired me to study th...”
     
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  • Myopathies — Alan Beggs, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Endocrine Myopathies
    “Alan Beggs and colleagues will identify gene mutations in zebrafish that cause congenital myopathies and will screen peo...”
     
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  • nemaline myopathy - Alan Beggs, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Endocrine Myopathies
    “Alan Beggs is working to uncover genes that cause nemaline myopathy.”
     
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  • CMT — Bogdan Beirowski, M.D., Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Beirowski is studying the loss of axons in Charcot-Marie-Tooth disease (CMT). (Axons are the long fibers through which n...”
     
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  • ALS – Michael Benatar, M.D., Ph.D., and Jonathan Katz, M.D.
    Funded: 03/01/17 through 02/28/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Integration of a mechanism to collect research-useful data through a clinical workflow within the electronic health r...”
     
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  • ALS — Michael Benatar
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"MDA funding has been absolutely critical for this study," Benatar said, noting that the "strength" of the study lies in...”
     
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  • DM – Andrew Berglund, Ph.D.
    Funded: 08/01/17 through 07/31/20
    Grant Announced: Summer 2017
    Disease Type: Myotonic Dystrophy (DM)
    “I think the myotonic dystrophy field has made great gains in understanding the mechanisms of this disease, and there a n...”
     
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  • MMD/DM - Andrew Berglund, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Myotonic Dystrophy (DM)
    “Andrew Berglund is investigating whether changing the shape of abnormal genetic material in type 1 or type 2 MMD can red...”
     
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  • DMD/BMD - Harold Bernstein, M.D., Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “(Left) A section of mouse leg muscle shows normal muscle fibers, with muscle cell nuclei shown in blue and aligned prope...”
     
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