Hope Through Research

At MDA, we take a big picture perspective across the full spectrum of neuromuscular diseases to uncover scientific and medical breakthroughs that accelerate treatments and cures. The power in our research approach is that we can often apply learnings from one disease to progress in others to bring urgently-needed answers to our families.

479 grants match your search

  • DMD/BMD — Tivorsan Pharmaceuticals
    Grant Announced: Additional Grants 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
     
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  • DMD/BMD — ARMGO Pharma
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • ALS — Bridge-to-Industry Training Program
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS — NeuRx Diaphragm Pacing System (DPS)
    Grant Announced: Additional Grants 2012
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • MTM — Valerion Therapeutics
    Grant Announced: Additional Grants 2013
    Disease Type: Endocrine Myopathies
     
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  • DMD — Catabasis Pharmaceuticals
    Grant Announced: Additional Grants 2012
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Favorable results in mouse studies could lead to clinical trials for CAT-1004 or CAT-1040 in people with DMD.”
     
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  • ALS — National Institutes of Health (NIH) Laboratory
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • ALS - Iron Horse Diagnostics
    Funded: 04/03/17 through 05/03/18
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Our prognostic test will be an essential tool to enhance drug development for ALS,” said Iron Horse Diagnostics Chi...”
     
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  • DMD — ReveraGen BioPharma
    Grant Announced: Additional Grants 2012
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • DMD — Halo Therapeutics
    Grant Announced: Additional Grants 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
     
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  • ALS — ALS Therapy Development Institute (ALS TDI)
    Grant Announced: Additional Grants 2013
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
     
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  • CMT - Charles Abrams, M.D., Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “"This project will generate new understanding of how mutations in the gene for the connexin 32 protein lead to central n...”
     
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  • DMD – Matthew Alexander, Ph.D.
    Funded: 02/01/18 through 01/31/21
    Grant Announced: Winter 2018
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Many drugs for neuromuscular diseases fail to win FDA approval, resulting in a large amount of wasted time and resources...”
     
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  • DMD - Matthew Alexander, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Alexander uses a variety of techniques, including the western gel film blot shown here, to identify expression of miR-48...”
     
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  • CMD - Douglas Anderson, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Congenital Muscular Dystrophy (CMD)
    ““The continued discovery and characterization of key regulators of skeletal muscle function, such as myoregulin, will ...”
     
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  • CMT - Anthony Antonellis, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Anthony Antonellis is studying how mutations in genes for certain enzymes lead abnormalities in CMT-affected cells. Char...”
     
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  • ALS - Stanley Appel, M.D.
    Grant Announced: Spring 2014
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Stanley Appel is studying how the immune system behaves in ALS. Amyotrophic Lateral Sclerosis (ALS)”
     
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  • ALS — Stanley H. Appel
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"In ALS, neurons do not die alone," Appel said. Injury to, and death of, the cells results from "crosstalk" among certai...”
     
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  • DMD/BMD — Zolt Arany
    Grant Announced: Summer 2010
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “"MDA has had an important impact on research in muscular dystrophy," Zolt said. "Without MDA support, we would not be ab...”
     
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  • ALS - Gary Armstrong, Ph.D.
    Grant Announced: Summer 2015
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Gary Armstrong’s research focus is on the synaptic defects that occur in the spinal cord and at the neuromuscular junc...”
     
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  • DMD/BMD — Atsushi Asakura, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Asakura uses an inverted microscope to capture images of satellite cells, which play essential roles in muscle regenerat...”
     
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  • ALS – Nazem Atassi, M.D., MSSc
    Funded: 12/01/17 through 11/30/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “One of the main roadblocks for ALS drug development is the lack of markers that tell us about drug efficacy in patients,...”
     
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  • LEMS - William Atchison, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Lambert-Eaton Myasthenic Syndrome (LEMS)
    “Using a mouse model of LEMS, Atchison will explore the means by which certain types of calcium channel proteins are recr...”
     
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  • ALS - Paul August, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “Paul August is using novel technology to develop a chip that will facilitate the testing of experimental therapies for A...”
     
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  • SMA - Tomoyuki Awano, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Spinal Muscular Atrophy
    “Using a confocal microscope, Awano views a neuromuscular junction in a mouse gastrocnemius muscle. On the computer monit...”
     
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  • CMT - Elisabetta Babetto, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Elisabetta Babetto will study whether manipulating the PHR1 protein pathway helps to preserve nerve fibers in mice with ...”
     
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  • Muscle disease - Mariah Baker, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Becker Muscular Dystrophy (BMD)
    “Mariah Baker will investigate how calcium is released in muscle cells, which may lead to treatment for a variety of diso...”
     
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  • Pompe - Celine Baligand, Ph.D.
    Grant Announced: Winter 2012
    Disease Type: Metabolic Myopathies
    “The pre-clinical optimization of new potential treatments and the evaluation of their efficacy and administration routes...”
     
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  • CMT - Robert Baloh, M.D., Ph.D.
    Grant Announced: Summer 2015
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Within the fields of ALS and CMT research, Robert Baloh’s specific focus is on using human genetics as a guide toward ...”
     
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  • OPMD - Ayan Banerjee, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Oculopharyngeal Muscular Dystrophy (OPMD)
    “Banerjee’s goal is to better understand how the PABN1 protein is regulated, in order to develop a better understanding...”
     
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  • ALS - Ellen Barrett, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “These images show motor nerve terminals in the hind limb of a healthy mouse (left) and that of an ALS-affected mouse (ri...”
     
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  • Mito. Myopathy - Antoni Barrientos, Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Mitochondrial Myopathies (MM)
    “Barrientos, pictured with collaborators Flavia Fontanesi and Jingjing Liu, notes that defects in an enzyme called cytoch...”
     
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  • MM - Antoni Barrientos, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Mitochondrial Myopathies (MM)
    ““The study of mitochondria is now a very ‘hot issue’ for both basic and clinical research, Antoni Barrientos says....”
     
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  • SMA - Gary Bassell, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Spinal Muscular Atrophy
    ““Our central hypothesis is that SMN protein plays a critical role in facilitating regulation of mRNA transport in moto...”
     
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  • BMD, DMD - Linda Baum, M.D., Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Becker Muscular Dystrophy (BMD)
    ““By using these human muscle cells to screen drug libraries to identify compounds that improve cell function, our aim ...”
     
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  • SMA — Lisa Baumbach, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Spinal Muscular Atrophy
    “Baumbach (front, right) with the other members of the lab team that discovered the X-linked gene for spinal muscular atr...”
     
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  • EDMD — Mary Baylies, Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Emery-Dreifuss Muscular Dystrophy (EDMD)
    “Like human muscle fibers, each fiber in a fruit fly (drosophila) is multinucleated and has a distinct size and shape. Un...”
     
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  • PP — Kurt Beam
    Grant Announced: Summer 2010
    Disease Type: Endocrine Myopathies
    “"Our MDA research project, 'voltage sensor for excitation-contraction coupling,' seeks to understand how skeletal muscle...”
     
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  • CCD — Kurt Beam, Ph.D.
    Grant Announced: Summer 2013
    Disease Type: Endocrine Myopathies
    “Beam uses electrical equipment to measure currents, and a confocal microscope to measure calcium inside cells.”
     
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  • DMD, BMD - Joseph Beavo, Ph.D.
    Grant Announced: Winter 2013
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “Recent work from Beavo and others strongly suggests that sildenafil ameliorates much of the dysfunction seen in older md...”
     
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  • Aaron Beedle, Ph.D.
    Funded: 02/01/17 through 01/31/20
    Grant Announced: Winter 2017
    Disease Type: Limb-Girdle Muscular Dystrophy (LGMD)
    “Aaron Beedle and colleagues are working to determine whether drugs that target a common intracellular pathway for cell g...”
     
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  • ALS - Asim Beg, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““The devastating impact that ALS has on patients and their families is a major factor that has inspired me to study th...”
     
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  • Myopathies — Alan Beggs, Ph.D.
    Grant Announced: Summer 2011
    Disease Type: Endocrine Myopathies
    “Alan Beggs and colleagues will identify gene mutations in zebrafish that cause congenital myopathies and will screen peo...”
     
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  • nemaline myopathy - Alan Beggs, Ph.D.
    Grant Announced: Winter 2016
    Disease Type: Endocrine Myopathies
    “Alan Beggs is working to uncover genes that cause nemaline myopathy.”
     
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  • CMT — Bogdan Beirowski, M.D., Ph.D.
    Grant Announced: Summer 2012
    Disease Type: Charcot-Marie-Tooth Disease (CMT)
    “Beirowski is studying the loss of axons in Charcot-Marie-Tooth disease (CMT). (Axons are the long fibers through which n...”
     
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  • ALS – Michael Benatar, M.D., Ph.D., and Jonathan Katz, M.D.
    Funded: 03/01/17 through 02/28/19
    Grant Announced: Additional Grants 2017
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    ““Integration of a mechanism to collect research-useful data through a clinical workflow within the electronic health r...”
     
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  • ALS — Michael Benatar
    Grant Announced: Summer 2010
    Disease Type: ALS: Amyotrophic Lateral Sclerosis
    “"MDA funding has been absolutely critical for this study," Benatar said, noting that the "strength" of the study lies in...”
     
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  • DM – Andrew Berglund, Ph.D.
    Funded: 08/01/17 through 07/31/20
    Grant Announced: Summer 2017
    Disease Type: Myotonic Dystrophy (DM)
    “I think the myotonic dystrophy field has made great gains in understanding the mechanisms of this disease, and there a n...”
     
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  • MMD/DM - Andrew Berglund, Ph.D.
    Grant Announced: Spring 2014
    Disease Type: Myotonic Dystrophy (DM)
    “Andrew Berglund is investigating whether changing the shape of abnormal genetic material in type 1 or type 2 MMD can red...”
     
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  • DMD/BMD - Harold Bernstein, M.D., Ph.D.
    Grant Announced: Winter 2011
    Disease Type: Duchenne Muscular Dystrophy (DMD)
    “(Left) A section of mouse leg muscle shows normal muscle fibers, with muscle cell nuclei shown in blue and aligned prope...”
     
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