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Research Grants

ACTIVE GRANTS, 1999

VIRGINIA

FUNDING PROGRAM LEGEND
(EMG) (GRG) (INT) (RF) (RG) (SG) (DG)	Earmarked Gift Genetics Research Grant Interim Grant Research Fellowship Research Grant Special Grant Research Development Grant

Blacksburg - Virginia Polytechnic and State University

Robert W. Grange, Ph.D.
(RG) Pathogenic mechanisms in Duchenne muscular dystrophy (DMD)
$ 64,011.00	7/1/99 - 6/30/00	Year 2
$ 67,279.00	7/1/00 - 6/30/01	Year 3

Summary: Researchers will test muscles from a new mouse model of DMD to more clearly define the processes by which muscle-wasting is initiated and maintained.

Charlottesville - University of Virginia

Yong Kim, Ph.D.
(RG) Lambert-Eaton syndrome (LEMS):  Autoimmunity to P-type calcium channels
$ 46,841.00	1/1/00 - 12/31/00	Year 3

Summary: Identification of autoantigens initiating and maintaining the autoimmune response in the LEMS and their role in the production of pathogenic autoantibodies impairing the motor and autonomic dysfunctions.

J. Randall Moorman, M.D.
(RG) Membrane electrophysiology of myotonic dystrophy (MMD) models
$ 60,000.00	7/1/99 - 6/30/00	Year 1
$ 60,000.00	7/1/00 - 6/30/01	Year 2
$ 60,000.00	7/1/01 - 6/30/02	Year 3

Summary: To understand the mechanism of MMD, a new kind of molecular disease model, researchers will systematically study genetically engineered mice.

Sonia H. Pearson-White, Ph.D.
(RG) The Sno proto-oncogene in the regulation of myogenesis
$ 55,000.00	7/1/99 - 6/30/00	Year 3

Summary: Researchers will test the hypothesis that the Sno proto-oncogene plays a role in the regulation of skeletal muscle regeneration after traumatic or neuromuscular disease injury.

(EMG) Restricted funds for research
$ 1,000.00	4/1/99 - 3/30/00	Year 1

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