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Washington - Children's National Medical Center Diana M. Escolar, M.D. (RG) Clinical trial of glutamine and creatine in Duchenne muscular dystrophy (DMD) $200,000.00 1/1/00 - 12/31/00 Year 1 Summary: Researchers will test the effects of glutamine and creatine to increase muscle strength in DMD. Eric Hoffman, Ph.D. (RG) Factors influencing efficiency of gene delivery to myogenic cells $50,000.00 7/1/99 - 6/30/00 Year 3 Summary: Methods of improving delivery of genes to skeletal muscle will be studied in an effort to facilitate gene therapy for Duchenne muscular dystrophy. Washington - Children's Research Institute Francisco Murillo, Ph.D. (DG) Molecular mechanisms of familial spastic paraparesis (FSP) $35,000.00 7/1/99 - 6/30/00 Year 1 $35,000.00 7/1/00 - 6/30/01 Year 2 Summary: The purpose of this project is to find the basic molecular mechanisms leading to the inherited motor neuron disorder known as FSP. Research for the genes responsible for this disease will be emphasized. Washington - Georgetown University Medical Center Sheridan Swope, Ph.D. (RG) Protein tyrosine kinases in myasthenia gravis (MG) and muscular dystrophy $65,702.00 1/1/00 - 12/31/00 Year 3 Summary: This project aims to study the regulation of proteins at the neuromuscular junction and dystrophin glycoprotein complex that are involved in MG and muscular dystrophies, respectively. Return to MDA Research Grants |
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