MDA Research Digest: Category by Disease Group

Research Digest
Inflammatory Myopathies

--- MDA Resources ---

--- Primary Scientific Literature ---

Mar. 02	Enzyme Evidence Points to Amyloid Beta in IBM Vattemi G et al. Presence of BACE1 and BACE2 in muscle fibres of patients with sporadic inclusion-body myositis. Lancet. 2001 Dec 8;358(9297):1962-4. [PubMed abstract] [Quest]
Nov. 01	Defective Gene Located for Rare Form of IBM Eisenberg I et al. The UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase gene is mutated in recessive hereditary inclusion body myopathy. Nat Genet. 2001 Sep;29(1):83-7. [PubMed abstract] [Quest]
July 01	Infection with AAV not a trigger, but a shield against myositis? Tezak Z et al. Adeno-associated virus in normal and myositis human skeletal muscle. Neurology 2000 Dec 26;55(12):1913-7. [PubMed abstract] [MDA Technical Summary]
July 01	A possible trigger for myositis: it's not one of the usual suspects Nagaraju K et al. Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies. Proceedings of the National Academy of Sciences U S A. 2000 Aug 1;97(16):9209-14. [PubMed abstract] [MDA Technical Summary]
Nov. 00	Enzyme Blockers May Prove Useful Against Inflammatory Myopathies Choi Y-C, and Dalakas MC (2000): Expression of matrix metalloproteinases in the muscle of patients with inflammatory myopathies. Neurology, 54(1):65-71. [PubMed abstract] [Quest]