Lou Gehrig’s Disease (Amyotrophic Lateral Sclerosis)

ALS Research Update: Spring 2015

Understanding the many roads that can lead to amyotrophic lateral sclerosis (ALS) is a painstaking but necessary prerequisite to development of disease-modifying treatments. Recently, several research teams have made contributions to this effort. A 2011 MDA career development grant to Adrian Israelson, who was then at the University of California, San Diego, was crucial to the finding that the MIF protein counteracts the effects of ALS-causing mutations in the SOD1 gene.

Genervon's 'Master Regulator' Drug Encourages ALS Community

Biopharmaceutical company Genervon has announced what it considers encouraging  results from a "compassionate use" trial of its experimental drug GM604 in a single patient with advanced  amyotrophic lateral sclerosis (ALS).

MDA President and CEO Takes the #ALSIceBucketChallenge

CHIGAGO, August 15, 2014 – Having a bucket of ice water dumped on your head may not seem dignified, but it is certainly helping MDA and other ALS-fighting organizations raise awareness and funds as the viral social media craze continues to sweep across America.  

Today, Steven M. Derks, President and CEO of the Muscular Dystrophy Association, joined the ranks of tens of thousands of people willing to get chilled in the ALS Ice Bucket Challenge.

New Forms of Genetic Testing Improve Diagnosis, Raise Questions

“Knowing, if not all, is almost all,” said Matthew Harms, a neurologist and neurophysiologist from Washington University in St. Louis, in his presentation on genetic testing for neuromuscular disorders at the 2014 MDA Clinical Conference, held in Chicago March 16-19.

Augie’s Quest To Transition from MDA to the ALS Therapy Development Institute

'Clump-Busting' Molecule Targets Misfolded Proteins in ALS

ALS Care Checklist Developed

Immune System Modulator in Development for ALS

DNA Damage in ALS

A failure to repair damaged DNA appears to play an important role in amyotrophic lateral sclerosis (ALS), an MDA-supported team of researchers reports.

Eighth Annual Tradition of Hope Gala Raises More Than $1.2 Million for MDA's Augie's Quest

MDA in Your Community

Grants