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Becker Muscular Dystrophy (BMD)
Definition - One of nine types of muscular
dystrophy, a group of genetic, degenerative diseases primarily affecting
voluntary muscles.
Cause - Insufficient production of dystrophin, a protein that
helps keep muscle cells intact.
Onset
- Adolescence or adulthood.
Symptoms - Generalized weakness
and wasting first affecting the muscles of the hips, pelvic area, thighs and
shoulders. Calves are often enlarged. BMD is similar to
Duchenne muscular dystrophy but often much less severe. There can be
significant heart involvement.
Progression
- Disease progresses slowly and with variability but can affect all voluntary
muscles. Most with BMD survive well into mid- to late adulthood.
Inheritance - X-linked recessive.
BMD primarily affects boys and men, who inherit the disease through their
mothers. Women can be carriers but usually exhibit no symptoms.