Muscular Dystrophies

MDA Awards $10 million in new Research Grants

CHICAGO, August, 27, 2015 — Prominent business and community leaders from across the country have been appointed to the Muscular Dystrophy Association’s Board of Directors. As members of the board, these 20 men and women will volunteer assistance and counsel to support MDA’s mission to fund lifesaving research, provide comprehensive care through its services and programs, and foster independence within its community.

Muscle disease - Colin Crist, Ph.D.

Colin Crist, an assistant professor in the department of human genetics at McGill University in Québec, Canada, was awarded an MDA research grant totaling $300,000 over three years to investigate a biological mechanism that determines whether skeletal muscle stem cells, which play an important role in muscle regeneration, self-renew or differentiate. Crist has identified inhibitors that control this functional “switch.” This work may inform muscular dystrophy therapy development.

 Funding for this MDA research grant began Aug. 1, 2015.

Muscle disease - Michael Kyba, Ph.D.

Michael Kyba, at the University of Minnesota in Minneapolis, was awarded an MDA research grant totaling $300,000 over three years to study the role of satellite cells in skeletal muscle regeneration. Kyba’s research to discover and study genes that regulate the regenerative potential of satellite cells will lead to a better understanding of skeletal muscle regeneration, with implications for our understanding of skeletal muscle regeneration in disease states and of the differences in muscle regenerative potential between individuals.

Becker Muscular Dystrophy Research Today

2015 Becker MD Conference Preview

MDA and Jiffy Lube® Team Up to Support the Fight Against Muscle Disease with Fourth Annual MUSCLE UP!SM Campaign

Muscle disease - Shihuan Kuang, Ph.D.

Shihuan Kuang, an associate professor of animal sciences at Purdue University in West Lafayette, Ind., has been awarded an MDA research grant totaling $253,800 over three years to investigate the use of low-oxygen conditioning of cells to improve stem cell-based therapies to treat muscular dystrophies.

Funding for this MDA research grant began May 1, 2014.

Muscle disease - Stephen Hauschka, Ph.D.

Stephen Hauschka, a professor of biochemistry at the University of Washington-Seattle, has been awarded an MDA research grant totaling $253,800 over three years to develop and test new “on-off” gene “switches,” also known as “regulatory cassettes,” to be used in gene transfer therapies to treat muscle disorders.

Funding for this MDA research grant began May 1, 2014.

Muscle disease - Mariah Baker, Ph.D.

Mariah Baker, a research associate at the University of Texas Health Science Center at Houston, has been awarded an MDA development grant totaling $152,073 over three years to study how the release of calcium molecules is triggered in muscle cells. Improved understanding of this process could have implications for treating a variety of muscle disorders.

Funding for this MDA research grant began May 1, 2014.

Drug Development for DMD: Fall 2014 Update

Drug development for Duchenne muscular dystrophy (DMD) is progressing on several fronts. Here are some updates as of early November 2014.

PTC is moving forward with ataluren

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