Definition - a muscle disease that interferes with the muscle cell's processing of ATP, the major energy molecule of the cell

Cause - a genetic defect in the myoadenylate deaminase enzyme, which affects the cell's ability to recycle ATP

Onset - adulthood

Symptoms - exercise intolerance, cramps and muscle pain; often no symptoms appear

Progression - not progressive

Inheritance - autosomal recessive, or caused by the contribution of a defective gene from each parent

Facts About Metabolic Diseases of Muscle